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Xiao Jian Zhong Tang Wan小建中汤丸

Xiao Jian Zhong Tang Wan小建中汤丸

Ingredients: Yi Tang (Maltosum) 562.5 mg Gui Zhi (Cinnamomi Ramulus) 562.5 mg Bai Shao (Paeoniae Radix Alba) 337.5 mg Zhi Gan Cao (Glycyrrhizae Radix Praeparata) 292.5 mg Sheng Jiang (Zingiberis Rhizoma Recens) 270 mg Da Zao (Jujubae Fructus) 225 mg

Specification: 0.19g/0.20g*200pills, 8 pills to be taken with water 3 times a day after meals

The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P < 0.05) was found for individual herb extracts, but XJZT showed protection of human lymphocytic DNA upon oxidative stress (P < 0.05). The in vitro DNA protection effect of XJZT was conferred by the synergistic effect of the herbs, while the individual herbs had no such effect.

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